To explore the association between rs822336 and PD-L1 expression, we determined the levels of PD-L1 mRNA and protein expression in human NSCLC cell lines carrying different rs822336 genotype, under basal conditions or following treatment with interferon gamma (IFN-ɣ) (Fig. 4 and Fig. S4). Here, CD274 is linked to non-small cell lung carcinoma.