EGFRmut HCC827G/G, H1975G/G and EGFRwt H460G/G, A549G/G, H1299C/C and H1437C/C cells were selected for further experiments based on their common histology (adenocarcinoma) and their different status of EGFR and rs822336. This evidence concerns the gene EGFR and adenocarcinoma.