INHBA and rheumatoid arthritis: Importantly, gene ontology analysis of the transcriptome of 10Upa-GM-MØ and 100Upa-GM-MØ revealed that the presence of Upa significantly (FDRq = 0.0) diminishes the expression of the pro-inflammatory “GM-MØ-specific” gene set (GSE188278) [43] (Fig. 2E), which includes genes like INHBA (Fig. 2F), and reduces the production of INHBA-encoded activin A (Fig. 2G), whose expression is particularly high in synovial macrophages from RA patients [16, 17].