The box plot in Fig. 6a shows that HNRNPA0, EFTUD2, PRPF19, SRSF2, SRSF7, SF3B1, SNRPE, SNRNP40, SNRPB2, SRSF1, HNRNPC, HNRNPA3, SRSF3, CPSF2, HNRNPR, HNRNPK, and PPIL1 had significant differences in the three immune characteristic T2D subtypes. This evidence concerns the gene HNRNPR and type 2 diabetes mellitus.