The box plot in Fig. 6a shows that HNRNPA0, EFTUD2, PRPF19, SRSF2, SRSF7, SF3B1, SNRPE, SNRNP40, SNRPB2, SRSF1, HNRNPC, HNRNPA3, SRSF3, CPSF2, HNRNPR, HNRNPK, and PPIL1 had significant differences in the three immune characteristic T2D subtypes. The gene discussed is HNRNPA0; the disease is type 2 diabetes mellitus.