KMT2C and neurodevelopmental disorder: Among many genes involved in this pathway, KMT2C (Lysine methyltransferase 2c), encoding a catalytic unit of the histone methyltransferase complex regulating mono- and di-methylation of histone H3 lysine 4 (H3K4me1 and H3K4me2), is reported as one of the genes causally associated with ASD and neurodevelopmental disorders (NDD).