CFTR and cystic fibrosis: Notably, compared with 16HBE14o- cell line which was heterologous for CFTR, the E protein could slightly augment the phosphorylation of JNK in a TLR2-dependent manner in CFBE41o- cells, a human CF bronchial epithelial cell line which expressed the almost undetectable fully glycosylated mature form of CFTR53 (Supplementary Fig. 12).