The virus could disrupt the epithelial integrity and exacerbate the inflammation in the airway epithelia, the first-line defense against viral infection.5 SARS-CoV-2 encodes four structural proteins - the Spike (S), Envelope (E), Membrane (M) and Nucleocapsid (N) proteins.6 The S protein mediates viral binding to the host receptor angiotensin-converting enzyme 2 (ACE2) and virus–cell membrane fusion. Here, ACE2 is linked to viral infectious disease.