Considering height and IGF-1 and their association with CRC risk and breast cancer risk, IGF-1 remained significantly associated with breast cancer risk (ORMVMR = 1.06, PMVMR = 0.049), while height remained significantly associated with colorectal cancer risk (ORMVMR = 1.06, PMVMR = 0.045). This evidence concerns the gene IGF1 and colorectal cancer.