CD4 and pneumocystosis: Our random effect models for SMD analysis of serum levels of CD4+ T cells [43, 49, 55, 56, 58–62, 74, 88, 91, 92], LDH [48, 55, 64, 65, 88], and BDG [45, 55, 59, 64, 92] in 12, 5, and 5 studies (respectively), indicated that serum levels of CD4+ T cells (SMD: -0.617; 95% CI:-1.122 to -0.111; I2: 95.1%;P = 0.000) and LDH (SMD: -0.089; 95% CI:-0.089 to 0.267; I2: 8.2%;P = 0.36) did not differ statistically between HIV/PCP-positive and HIV-positive PCP-negative patients.