Since M2 macrophage cell infiltration was higher in WT patients with high SNHG15 expression, revealing its potential molecular mechanism on tumor cells; GSEA: "HALLMARK-PI3K-AKT-MTOR -SIGNALING", "Glutamatergic synapse" and "Glycolysis" pathways were highly enriched in the highly expressed SNHG15 tumor cells. This evidence concerns the gene AKT1 and neoplasm.