DHCR7 and breast cancer: Furthermore, we used an ROC curve to evaluate and validate the diagnostic value of DHCR7 and found that the area under the curve (AUC) was 0.83 (95% CI = 0.81–0.86, P < 0.001) in the TCGA-BRCA dataset and that DHCR7 was up-regulated in BC (Figure 5H).