MAN1C1 and breast cancer: Forest plots indicated that 8 EMRGs were considered a risk factor for BC, including DHCR7, ADM, EIF2AK1, GMDS, LPCAT1, MGAT4B, TKT, and RIAD (HR > 1, P < 0.05), and 14 EMRGs acted as a protective prognostic factor for BC, including ALDH18A1, ANG, CDO1, DMD, CHST15, GYG2, GYPC, MAN1C1, RRBP1, ST6GALNAC6, TRAK1, MLXIPL, FASN, and GNG12 (Figure 5F).