In our study we elucidated the effect of DHCR7 on the ROS and MMP levels of BC cells; we found that DHCR7 knockdown increased ROS levels and decreased MMP in MDA-MB-231 cells, indicating that DHCR7 is a candidate oncogene in BC, which is consistent with the results of previous studies. The gene discussed is DHCR7; the disease is breast cancer.