Moreover, another study on the role and mechanism of UCHL1 in cardiac hypertrophy induced by pressure overload revealed that the expression of UCHL1 was upregulated in hypertrophic heart, while the overexpression of UCHL1 could inhibit the growth of fibroblasts, and the inhibition of growth was not related to apoptosis. The gene discussed is UCHL1; the disease is cardiac hypertrophy.