In accordance with the revised guidelines of the World Health Organization (WHO) on the use of the urinal lipoarabinomannan test (TB-LAM) for the diagnosis of tuberculosis (TB), it is reliably recommended to use this test in HIV-positive patients with a CD4 count of less than 100 cells/μL, regardless of the presence of signs and symptoms of tuberculosis [117]. This evidence concerns the gene CD4 and tuberculosis.