Rhubarb acid was the first identified FTO inhibitor that helps overcome tumor resistance to methylated anticancer drugs.[176] The ethyl ester form of meclofenamic acid inhibits the growth of glioblastoma stem cells.[177,178] R-2-hydroxyglutarate (R-2HG) inhibits the proliferation of leukemia cells.[179] The study of m6A modifications in GC provides new insights into the molecular treatment of tumors. This evidence concerns the gene FTO and leukemia.