The interaction of IGF2BP1 protein and c-Myc mRNA is enhanced by the upregulation of lncRNA GLCC1, which promotes the stabilization of c-Myc mRNA, and its knockdown contributes to apoptosis in GC cells.[136] IGF2BP3 increases GC migration and invasion via the formation of a ternary complex of circFNDC3B-IGF2BP3-CD44 mRNA.[140]. This evidence concerns the gene IGF2BP1 and gastric cancer.