EN1 and skin neoplasm: Wound healing fibroblast clusters included populations displaying high Spp1, En1, Mest, and Crabp1 expression, which were not consistently observed in skin cancer CAFs; on the other hand, skin cancer CAFs showed fibroblast populations expressing high levels of complement, Meg3, Lrrc15, and Rgs5, which were not reported in wound healing CAFs.