IDO1 and melanoma: Matrix CAFs in SCC, BCC, and melanomas expressing high levels of COL1A1, COL1A2, COL3A1, LUM, POSTN, TNC, COL11A1 and PTGDS were a larger constituent of benign tumors, while higher numbers of iCAFs expressing MMP1, MMP3, IL6 CXCL8, and IDO1 and different chemokines were correlated with advanced disease (Agnes et al., 2023).