FOLH1 and pachyonychia congenita: In fact, PSMA-PET/CT has proven to have higher specificity and positive-predictive value in detecting sites of disease that are not visible in conventional imaging.21,22 Such findings may suggest the potential creation of two further subgroups in our study: patients with non-metastatic, high risk PC submitted to conventional staging of disease, and patients with non-metastatic, PSMA-negative, high risk PC.