CTNNB1 and metabolic dysfunction-associated steatotic liver disease: Similarly, the role of Wnt/beta catenin signaling - where the binding of a Wnt ligand with a surface receptor (Fzd) and a co-receptor (LRP5/6) is responsible for the stabilization of beta/catenin, its nuclear translocation and Wnt target gene expression - in NAFLD development has been described, as recently reviewed in detail by Harini et al.