HOXA10 and leiomyoma: To assess spatial differences in the expression of a gene transcript with known relevance for endometrial function in the presence of a localized lesion, such as leiomyoma, the expression of HOXA10 was evaluated in 30 paired biopsies obtained at different endometrial sites in the same patient: 15 were collected in the area overlying the leiomyoma and the other 15 were from a remote location overlying the normal myometrium.