The following loci were associated to blood pressure phenotypes (diastolic, systolic or hypertension): SYNPO2L, KCNQ1, MYL2, NDRG2, MYH6, SRL, GOSR2, GATA6, HSPB7, RNF11, EFEMP1, FNDC3B, NME9, PRDM6 and PLN. Finally, SYNPO2L, TBX5, MYH6, GOSR2, PITX2 and CDKN1A were associated to cardiac arrhytmias. The gene discussed is EFEMP1; the disease is hypertensive disorder.