As TTBK2 is essential for initiating cilia assembly, it is not surprising that a pathogenic mutation of TTBK2 leads to a neurological disorder known as spinocerebellar ataxia 11 (SCA11), characterized by atrophy of the Purkinje cells of the cerebellum (Bowie et al., 2018; Bashore et al., 2023). The gene discussed is TTBK2; the disease is nervous system disorder.