TPO and memory impairment: Ten of those AOPs have been endorsed by the OECD WNT/WPHA: AOP ID 6 describing antagonist binding to PPARα leading to body-weight loss, AOP IDs 23 and 25 linking androgen receptor agonism and aromatase inhibition respectively to reproductive dysfunction, AOP ID 42 linking thyroperoxidase (TPO) inhibition to decreased cognitive function, AOP ID 54 linking Na+/I− symporter (NIS) inhibition to learning and memory impairment, and AOP IDs 155–159 linking thyroperoxidase and deiodinase inhibition to impaired swim bladder inflation in fish.