In KRAS mutated cases of CRC, our results demonstrated that high P4HA2 expression was the only significant poor prognostic indicator regarding DFS (p = 0.013) using univariate analysis (Fig. 2) as well as in multivariate analysis adjusted to age and sex (p = 0.028; HR = 16.1; 95% CI 1.358–192.310) (Table 4). The gene discussed is P4HA2; the disease is colorectal carcinoma.