Only Kim et al. compared the functional decline between NSIP and UIP, reporting a better outcome after immunosuppressive treatment for NSIP compared to UIP (15% FVC improvement in 5/12 NSIP cases treated with CCS and CYC, compared to no improvement in the 5 UIP patients and a decrease in the CRP score after treatment only in the NSIP group) [26]. This evidence concerns the gene CRP and idiopathic pulmonary fibrosis.