CD226 and myasthenia gravis: Although MR analysis did not identify any genetically predicted gene expression causally linked to MG risk after FDR correction (full MR results in Additional file 2: Table S5), we observed similar pattern for CD226 expression with MG susceptibility (OR = 0.595; 95% CI 0.403–0.877; P = 8.754 × 10–03) (Additional file 1: Figure S3).