In the MG+si-NONMMUT004552.2 group (P < 0.001), the number of apoptotic MC3T3-E1 cells significantly decreased in response to MG, which was restored following the transfection of miR-15b-5p inhibitor or Syne1 (P < 0.05) (Fig. 4B). This evidence concerns the gene SYNE1 and myasthenia gravis.