There was also a significant reduction in tissue resident memory (TRM) CD69+CD103+CD8+ T cells in the lungs of the IAV→SFV co-infected group (Fig. 7f), and an apparent presence of IAV-specific CD69+CD103- and CD69+CD103+ TRM cells42 in the brain across all the experimental groups, regardless of modality of infection. The gene discussed is ITGAE; the disease is infection.