The expression of major histocompatibility complex I (MHC I) determines the immune antitumor response.[34] Hence, we analyzed the sequencing results of 149 patients, and Figure S3 (Supporting Information) shows that the expression of MHC class I chain‐related proteins A and B (MICA and MICB) was significantly upregulated in HCC patients. Here, MICB is linked to hepatocellular carcinoma.