CD36 and lip and oral cavity carcinoma: Furthermore, we found an increased metastatic area of LNs in HFD groups (Figure S3C,D, Supporting Information), which is in accordance with a previous study that HFD specifically boosted the metastatic potential of CD36+ metastasis‐initiating cells in oral cancer.[22] Together, these results suggest that HFD contributes to lymph node metastasis, which may be attributed to the increased fatty acids level and nutrient availability in lymph nodes.