In addition, when neurons were cultured in media diluted 1:1 with supernatant of LPS‐stimulated BV2 cells or microglia from AD mouse models for 48 h, FCM analysis showed that RAP treatment (20 μg/μL) dramatically inhibited the apoptosis of neurons in contrast to the control (Figure 4E,F). The gene discussed is LRPAP1; the disease is Alzheimer disease.