PDCD1LG2 and colonic neoplasm: In addition, recent studies have reported that PD‐L2 expressed by dendritic cells (DCs) can also modulate tumor immunity and attenuate the sensitivity of tumors to immunotherapy.[43] Our transcriptome data found that Taz can also upregulate PD‐L2 on colon tumor cells; however, despite this upregulation at the transcript level, PD‐L2 expression remains low at the protein level.