Thus, an analysis of mRNA expression data from The Cancer Genome Atlas (TCGA) (dataset ID: TCGA.COADREAD.sampleMap/HiSeqV2) were performed to verify our results and revealed that the level of DKK4 expression was higher in cancer tissues than in normal tissues and was positively correlated with advanced diseases (Fig. 1I; and Supplementary Fig. S1H‒J). This evidence concerns the gene DKK4 and cancer.