ALDH2 and Alzheimer disease: To determine if the ALDH2 rs671 A-allele is positively associated with an increased number of Aβ plaques, we immunostained amyloid plaques in eight regions from 44 postmortem brains with AD (18 with genotype GG, 18 GA, and 8 AA) (Supplementary Table 4, Supplementary Data 1).