No higher risk was found among GA or AA genotypes for tau hyperphosphorylation, neuritic plaque accumulation, average Everyday Cognition (ECog) score (Fig. 1a), or other co-neuropathologies including Lewy bodies, Braak staging of Parkinson’s disease, TDP-43 pathology, Primary age-related tauopathy, and Cerebral amyloid angiopathy (Supplementary Table 3) (Neuropathological evaluation—Supplementary Methods). This evidence concerns the gene TARDBP and cerebral amyloid angiopathy.