mTORC1 activation of CD3+, CD4+, and CD8+ T cells of lupus-prone B6.TC/Rab4AQ72L mice was reversed by the inactivation of Rab4A in T cells of B6.TC/Rab4AQ72L-KO mice (Fig. S5). This evidence concerns the gene CD8A and systemic lupus erythematosus.