To reveal the molecular mechanism associated with tumor growth inhibition by nuclear Hpa2, we extracted total RNA from tumors produced by control (#2, #5, #6) and Hpa2-Nuc (#27, #31) cell clones and employed RNAseq methodology to reveal genes regulated by nuclear Hpa2 (Hpa2-Nuc). The gene discussed is HPSE2; the disease is neoplasm.