Emerging evidence suggest that various components of the TGFβ pathways have been frequently reported as altered in the pathogenesis of preeclampsia (PE) (Venkatesha et al., 2006; Haider et al., 2017; Zhao et al., 2020b; Deng et al., 2023), and might be potential therapeutic targets for intervention. Here, TGFB1 is linked to preeclampsia.