Considering the previous report that DYRK3 regulates mTORC1 signaling through the modulation dynamin-related protein 1 (DRP-1) under radiation stress, consequently promoting glioblastoma progression (3), it could be hypothesized that DYRK3 also has an oncogenic feature in other types of cancer, including melanoma skin cancer. This evidence concerns the gene DYRK3 and cancer.