Among the different cancer cell lines tested, including human cervical carcinoma cells (HeLa), human embryonic kidney cells (HEK), human prostate cells (RWPE-1), and melanoma cell lines (SK-Mel-28, SK-Mel-5, UACC257, and UACC62), the highest expression of DYRK3 was observed in melanoma cell lines. This evidence concerns the gene DYRK3 and melanoma.