Both SK-Mel-28 tumors expressing p62-T269E or DYRK3 reached an average volume of 235.4 ± 56.8 or 238.5 ± 28.6 mm3, respectively, showing about 1.9-fold or 3.4-fold higher tumor volume compared to mock-transfected SK-Mel-28 or p62-T269A-expressing SK-Mel-28 tumors. This evidence concerns the gene SQSTM1 and neoplasm.