CD8A and neoplasm: Among lymphocytes, tumor CXCL9/10 expression in both LUAD and LUSC showed strong positive correlations with the infiltration of both CD8+ T cells and CD4+ Th2 effector T cells and a weak association with CD4+ Th1 effector T cells, consistent with the established role of the CXCL9/10-CXCR3 axis in T cell recruitment14,16 (Figures 1C, 1D, and S1A).