In cancer cells with abnormal expression of the cysteine transporter solute carrier family 7 member 11 (SLC7A11), upon binding to glucose starvation, cysteine uptake is high and cysteine is reduced to cysteine, depleting the NADPH pool and leading to the accumulation of large intracellular disulfide molecules and rapid cell death.[6,7] However, the nature of this cell death remains unknown. Here, SLC7A11 is linked to cancer.