The included indicators were NT-proBNP, SBP, DBP, HR, FS, EF, LV, LA before treatment; gender, age, weight, and BMI before and after treatment; whether to use diuretics intravenously, whether there is hypertension, whether there is atrial fibrillation, whether there is diabetes, whether there is coronary heart disease, whether there is COPD, whether there is a history of smoking and drinking, HF management methods, past tumor treatment methods, and cancer types. This evidence concerns the gene NPPB and chronic obstructive pulmonary disease.