We also identified previously known FOXL2 nuclear interactors, namely, signal transducer and activator of transcription 3 (STAT3), suppressor of Ty 16 homolog (SUPT16H), alpha-thalassemia/mental retardation, X-linked (ATRX), SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2 (SMARCD2), and x-ray repair cross complementing 6 (XRCC6) (52). This evidence concerns the gene STAT3 and alpha thalassemia spectrum.