To date, KRT18 [47], KRT19 [48], KRT8 [49], SFN [50], CLDN7 [51], FKBP4 [52], CCND1 [53], ELOVL5 [54], RHOD [55], SLC7A5 [56], MED24 [57], TPBG [58], AQP3 [59], OVOL2 [60], CISH [61], STC2 [62], PMAIP1 [63], and AREG [64] have been reported to be highly expressed in a variety of cancers and associated with the promotion of cancer cell growth, proliferation, migration and invasion. The gene discussed is PMAIP1; the disease is cancer.