Since, in our model, NK3R‐induced kiss1 activation in the MePD results in the suppression of pulsatile LH secretion, like the effect of TMT exposure, a stressor, on LH pulses and NK3R antagonism blocks the inhibitory effect of TMT on LH pulses, which occurs by preventing MePD kiss1 activation, this suggests that activation of MePD kiss1 signalling may be anxiety‐inducing in OVX mice exposed to stress. Here, PLOD1 is linked to Anxiety.