GTPBP4 and infection: The WT mice infected with FMDV started to die at 3 d post-infection (dpi) and all mice died by 4 dpi, while the Gtpbp4± mice infected by FMDV started to die at 3 dpi and survived 20% at 7 dpi, indicating that GTPBP4 deficiency decelerated FMDV-induced the death of mice (Figure 2C).