2022). Consistent with the marked changes in proteinuria, MGN rats had significantly increased urinary protein level (p < 0.01; Figure 2(A)). Additionally, the level of ALB was significantly decreased (p < 0.01; Figure 2(B)) with increased levels of BUN, SCr, TC and TG (p < 0.01; Figure 2(C–F)) compared with NC rats. The gene discussed is ALB; the disease is idiopathic membranous glomerulonephritis.