Western blot analysis revealed significantly upregulated expression levels of NF-κB p65, IKKβ, p-IKKβ, ICAM-1, VCAM-1, MCP-1 and E-selectin in MGN rats compared with the NC rats (p < 0.01; Figure 8(B–H)). The gene discussed is IKBKB; the disease is idiopathic membranous glomerulonephritis.