Western blot analysis showed that the expression levels of Nrf2 and its downstream antioxidative enzymes, NQO1 and HO-1, were significantly downregulated in MGN rats compared with the NC rats (p < 0.05, p < 0.01; Figure 6(B–D)). This evidence concerns the gene NFE2L2 and idiopathic membranous glomerulonephritis.