NFKB1 and idiopathic membranous glomerulonephritis: Moreover, the current study found that DG treatment inhibited the NF-κB signalling pathway, with DG-treated MGN rats displaying decreased NF-κB p65, IKKβ and p-IKKβ expression levels and reduced NF-κB p65 nuclear translocation, indicating that the anti-inflammatory effects of DG are mediated through the suppression of the NF-κB signalling pathway.