When analyzed together, glomeruli from patients with AS, FSGS, and MN showed a decreasing trend of expression of genes highly enriched for SRP-dependent cotranslational protein targeting to membrane, selenocysteine synthesis, and regulation of expression of SLITs and ROBOs, among others (Figure 5C and Supplemental Data Set 6). Here, UCN2 is linked to focal segmental glomerulosclerosis.