TNF and inflammatory bowel disease: Currently, management for IBD is characterized by a multifaceted strategy that encompasses interventions from lifestyle modifications (specific diets, stress management, regular exercise), pharmacological therapy (corticoids, immunomodulators), biological therapies (anti-TNF agents, anti-integrins, anti-IL-12/23) and constant surveillance and monitoring of the patient. IBD significantly impacts patients' quality of life and social functioning, both physically and emotionally.