Recently, proteins that, when mutated in mice, cause globozoospermia have been discovered, including DPY19L2, FAM209, FAM71F1, FAM71F2, GBA2, GOPC, PDCL2, PICK1, SPACA1, SSMEM1, and ZPBP1 (4–13). This evidence concerns the gene ZPBP and Globozoospermia.