For example, lncRNA AGAP2-AS1 has been demonstrated to recruit the enhancers of zeste homolog 2 (EZH2) and LSD1 to the promoter regions of KLF2 and large tumor suppressor 2 (LATS2), thus suppressing the transcription of KLF2 and LATS2 and promoting the progression of non-small cell lung cancer (Li W. et al., 2016). Here, EZH2 is linked to non-small cell lung carcinoma.