PTEN and infection: In cases of infection with GI.1 and GI.2, upregulation of miR-21 was accompanied by decreased levels of PTEN (8.5-fold reduction, 88% reduction, vs. control, p = 0.001 and 6-fold reduction, 84% reduction, vs. control, p = 0.002, respectively; Figure 1B) and PDCD4 (71.4-fold reduction, 98.6% reduction, p = 0.0002 and 273.4-fold reduction, 99.6% reduction, p = 0.0001, respectively; Figure 1C).