Studies conducted by Strowitzki et al. have substantiated the efficacy of DNG (at a dosage of 2 mg/day) in alleviating postoperative endometriosis-related pain, comparable to the outcomes observed with GnRH-a (Strowitzki et al., 2010; Strowitzki et al., 2012). The gene discussed is GNRH1; the disease is endometriosis.