Among these differentially expressed genes, 10 genes (NF2, TAOK2, TAOK3, STK4, MOB1A, MOB1B, LATS2, TEAD1, TEAD2 and TEAD4) were upregulated, whereas eight genes (WWC1, TAOK1, FRMD6, SAV1, LATS1, YAP1, TAZ and TEAD3) were downregulated in melanoma (Figure 2A). The gene discussed is STK4; the disease is melanoma.