As another important deafness-related gene, mitochondrial gene MT-RNR1, a meta-analysis demonstrated pooled prevalence in the general population for MT-RNR1 gene mutations (m.1494C>T, m.1555A>G, and m.7445A>G) was 2% (1%–4%) at 99%, which makes routine screening in high-risk Chinese populations justified [14]. The gene discussed is MT-RNR1; the disease is deafness.